Endogenous erythroid colony growth in polycythaemia vera

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JAK2V617F mutation and endogenous erythroid colony formation in patients with polycythaemia vera.

PURPOSE The purpose of this study was to investigate the frequency of JAK2V617F gene mutation in patients with polycythemia vera (PV) and to compare the results with the presence of endogenous erythroid colony (EEC) formation. METHODS Peripheral blood and bone marrow samples of 28 patients with PV were analyzed. The diagnosis of PV was established according to the bone marrow criteria of the ...

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Erythroid colony growth from peripheral blood and bone marrow in polycythaemia.

Erythroid colony growth in the presence and absence of erythropoietin was compared in 23 patients with primary proliferative polycythaemia (PPP), nine with idiopathic erythrocytosis, 10 with secondary polycythaemia, 15 with pseudopolycythaemia and in 76 normal subjects. Erythroid colonies growing without erythropoietin stimulation (endogenous erythroid colonies) from peripheral blood (BFU-E) we...

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Identification of masked polycythemia vera from patients with idiopathic marked thrombocytosis by endogenous erythroid colony assay.

We used the methylcellulose-culture technique to determine the utility of the erythroid progenitor growth in vitro from nonadherent T-depleted bone marrow and peripheral blood cells in distinguishing polycythemia vera (PV) from essential thrombocythemia. Thirty patients with PV (group A) and 30 patients who presented with idiopathic marked thrombocytosis with platelet count greater than 1,000 x...

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Peripheral gangrene in polycythaemia vera.

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Joint Complaints in Polycythaemia Vera.

The reported incidence of gout and hyperuricaemia in polycythaemia vera has varied in different series. Thus Tinney, Polley, Hall, and Giffin (1945) reported clinical gout in 4 7 per cent. of 168 cases, Videbaek (1950) in 9 per cent. of 125 cases, and Lawrence, Berlin, and Huff (1953) in 7 per cent. of 159 patients, and unspecified arthritis in a further 14 per cent. On the other hand, Wasserma...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2001

ISSN: 0007-1048

DOI: 10.1046/j.1365-2141.2001.03057.x